The functional characterization of proteins is elusive because proteins
have flexible structures, transiently existing in a continuum of structural
and functional states. The SeraFILE™ surface library affords high-resolution
partitioning of complex protein extracts into highly differentiated
fractions.
Along with conventional gel-based investigations, molecular profiling
combinations can also include bio-catalytic activities and protein-protein
interactions. Such multi-faceted characterizations are unique in the
systems biology industry.
ProFACT offers a comprehensive suite of molecular profiling services
readily integrated with other "omics" data for biomarker and drug
target discovery.
Introduction to Molecular Profiling Services
ProFACTs Molecular Profiling Services include: SeraFILE™, for reduction of
protein complexity and sub-proteome creation; Rational Proteome
Prospecting™, to enrich and isolate functional activity; Conformerics™, to
generate drug screening assays based on enzyme sub-states or conformers; and
Rational Genome to Proteome Prospecting™, for prospecting into protein
expression based on gene expression data.