ENPP2 antibody - 100 µg

https://www.labm.com/web/image/product.template/96639/image_1920?unique=df09146
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: ectonucleotide pyrophosphatase
phosphodiesterase 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 100 kDa
Uniprot: Q13822
Gene id:
Background: Hydrolyzes lysophospholipids to produce lysophosphatidic acid(LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.
Field of research: Immunology, Cardiovascular, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:20-1:200
Target: ENPP2
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat

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222.50 €

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