CXXC5 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: CXXC finger 5
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 35-40 kDa
Uniprot: Q7LFL8
Gene id: 51523
Background: May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells(By similarity). Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. Transcription factor. Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions(4% oxygen), as well as normoxia conditions(20% oxygen)(PubMed:23303788). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ(PubMed:23303788).
Field of research: Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: CXXC5
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: CXXC finger 5
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 35-40 kDa
Uniprot: Q7LFL8
Gene id: 51523
Background: May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells(By similarity). Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. Transcription factor. Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions(4% oxygen), as well as normoxia conditions(20% oxygen)(PubMed:23303788). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ(PubMed:23303788).
Field of research: Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: CXXC5
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat